LIPITOR LIPITOR LIPITOR SAVE SAVE SAVE CHOLESTOR CHOLESTOR CHOLESTOR ATOPITAR ATOPITAR ATOPITAR PRO-STATIN PRO-STATIN PRO-STATIN LIPIGET LIPIGET LIPIGET DESCOL DESCOL DESCOL CALIPTROL CALIPTROL CALIPTROL LIPIDIP MINILIP MINILIP RIDLIP RIDLIP RIDLIP DELIP DELIP MOMENTIUM MOMENTIUM MOMENTIUM ZEPITOR ZEPITOR LIPIREX LIPIREX LIPIREX VASTOR VASTOR VASTOR ASTAT ASTAT LIPIVASTIN LIPIVASTIN LIPIVASTIN TROVAS TROVAS VASCLEAR VASCLEAR ATORVA ATORVA MEDILIP ATASTAN ATORSCOT ATORSCOT ATORSCOT SENSICON SENSICON SENSICON COLSTAT COLSTAT ATORLIP ATORLIP LASTOLIP LASTOLIP LASTOLIP LASTOLIP LIPIDIN LIPIDIN LIPIDIN LIPIDIN MEGAVASTIN MEGAVASTIN LOVA STATOR TORLIP 3H TORLIP 3H DEROT DEROT DEROT LIPIFAL LIPIFAL LIPIFAL ORVA ORVA ORVA ORVA LIPOTRIM LIPOTRIM LIPOTRIM LIPISTAT LIPISTAT REDUSE REDUSE REDUSE ROVAX ROVAX TAVIST TAVIST ERAVAS SAFEHEART SAFEHEART TAVAS TAVAS TAVAS ALTOLIP ALTOLIP ALTOLIP ATRONIL ATRONIL ATRONIL ATORVASTIN ATORVASTIN LIPILOW LIPILOW LIPILOW LIPVAS LIPVAS VOZAR VOZAR VOZAR ASTATIN ASTRA ASTRA CARDISTATIN CARDISTATIN ROSTINOX ROSTINOX SNOLIP SNOLIP UNIVASTIN AMLAT AMLAT AMLAT STAT A STAT A ETAR ETAR FOPSEC FOPSEC FOPSEC GENOVAX GENOVAX GENOVAX GENOVAX OSCAR OSCAR OSCAR XTOR XTOR ATEASE ATEASE ATEASE ATEASE COMBITROL COMBITROL CHOLEIN CHOLEIN CADWIN CADWIN ATOREX ATOREX ATRATA ATRATA COLEZAF COLEZAF AM DESCOL AM DESCOL AM DESCOL AM DESCOL AM DESCOL AM DESCOL AM DESCOL AM DESCOL CADUET CADUET LASTOLIP EZ LASTOLIP EZ RENORM RENORM AMLOTIN AMLOTIN AMLOTIN LIPIGET EZ AMTORIN AMTORIN AMTORIN PLUS BVASTA BVASTA AMSTATIN AMSTATIN ATOZET CO-ATORAP CO-ATORAP CO-ATORAP CO-ATORAP HYPERSTATIN LYTRON RATOR PLUS RATOR PLUS RATOR PLUS RATOR PLUS RATOR PLUS TAVIST PLUS TAVIST PLUS TAVIST PLUS TAVIST PLUS TAVIST PLUS TAVIST PLUS A-TIN AMOSTIN AMOSTIN ATROLEAD ATROLEAD ATROLEAD CORSAFE CORSAFE LIPICA LIPICA LIPICA LIPICA PLUS LIPICA PLUS LIPICA PLUS LIPICA PLUS LIPICA PLUS LIPICA PLUS LIPICA PLUS LIPOTREX MOMENTIUM-PLUS VASTAPINE VASTAPINE AMOSTATIN AMOSTATIN ATORSAN ATORSAN ETORTIN TORSTAN A-CHOLE A-CHOLE CATRIL CATRIL CATRIL CORSAFE-AT CORSAFE-AT LOCHOL LOCHOL LOCHOL RAYTOR RAYTOR RAYTOR VASSODIP VASSODIP VASTA VASTA VASTA VASTOR-AM VASTOR-AM WINSTOR WINSTOR WINSTOR ZETAB-PLUS E-STAT E-STAT A-VAST ATOSTAT AVAST AVAST LIPAM LIPAM SEMOSTATIN SEMOSTATIN SEMOSTATIN SURVIVE-AT PLUS SURVIVE-AT PLUS CAPRISK ATORIN ATORIN ATRACHOL ATRACHOL AVOTIN KOLMARK KOLMARK KOLMARK LOW VASE LOW VASE AV AV LIPIGAN LIPIGAN XETROL XETROL AVASCAR PLUS AVASCAR PLUS AZTOR EZ LOVAS

Dose: 10 to 80 mg
Single Dose: 45 (45)
Frequency: 24 hourly
Route: PO
Instructions:

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Instructions: Not recommended in this age group

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Atorvastatin Calcium is the derivative of Atorvastatin. It is of Synthetic origin and belongs to Pheynylcarbomoyli. It belongs to HMGCoA reductase inhibitor pharmacological group on the basis of mechanism of action and also classified in Antilipemic Agent pharmacological group.The Molecular Weight of Atorvastatin is 1208.42. Its pKa is 4.6.

Atorvastatin is contraindicated in conditions like Hypersensitivity,Pregnancy,Breast feeding,Actinic keratosis.

The symptomatic adverse reactions produced by Atorvastatin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Flatulence, Weakness, Headache, Diarrhea, Fever, Myalgia, Constipation, Insomnia, Abdominal pain, Skin rashes, Blurred vision, Pharyngitis, Dyspepsia, Malaise, Asthenia, Arthralgia, Elevation of liver enzymes, Myopathy, Backache, Increased intracranial pressure, GI disturbance, Sinusitis.

Atorvastatin is primarily indicated in conditions like Familial hypercholesterolaemia, Homozygous familial hypercholesterolemia, Hypercholesterolaemia, Hyperlipoproteinaemia, Hypertriglyceridaemia, NSAID-associated gastric and duodenal ulcers and duodenal errosions.

Atorvastatin is known to interact with other drugs, the details of drug interactions is as follows:DrugDetailsSeverityOnsetManagementAliskirenAmprenavirAmprenavir possibly increases plasma concentration of Atorvastatin. ADVICE: Avoid concomitant use. MajorCimetidine (HCl)Cimetidine may decrease the metabolism of Atorvastatin. ModeratePatients who require concomitant thaerapy should be monitored for altered antihypertensive response if Cimetidine is introduced or discontinued, or when its dosage is modified.Colestipol (HCl)Cyclosporin ACyclosporin may increase the serum concentration of Atorvastatin. MajorMonitor altered effects (eg, increased serum CPK, myopathy, rhabdomyolysis) of Atorvastatin if Cyclosporin is introduced or discontinued, or when its dosage is modified.DigoxinAtorvastatin possibly increases plasma concentration of Digoxin.ErythromycinErythromycin may decrease the metabolism, via CYP isoenzymes, of Atorvastatin. Possible increased risk of myopathy when atorvastatin given with erythromycin.ModerateWhen coadministration of a Macrolide antibiotic and an HMG-CoA reductase inhibitor is necessary, consider using a combination which appears to hold the lowest risk for the development of rhabdomyolysis. Azithromycin, Dirithromycin, and Spiramycin can probably be used safely (ie, no increased risk of side effects) with any HMG-CoA reductase inhibitor. Neither Fluvastatin, Pravastatin, nor Rosuvastatin would likely be affected by Macrolides.Mibefradil (Di HCl)Nicotinic AcidIncreased risk of myopathy when statin (e.g Atorvastatin) given with nicotinic acid (applies to lipid regulating doses of nicotinic acid.RepaglinideAtorvastatin may increase repaglinide concentrations by decreasing metabolism. Warfarin (Na)Atorvastatin may enhance the anticoagulant effect of Warfarin. Moderate (Sequence important)Patients who require concomitant thaerapy should be monitored for altered response whenever Warfarin is introduced or discontinued, or when its dosage is modified. Dosage adjustments of Warfarin may be needed. These interactions are sometimes beneficial and sometimes may pose threats to life. Always consult your physician for the change of dose regimen or an alternative drug of choice that may strictly be required.

Drug should not be given to Paediatrics, Pregnant Mothers, and patients suffering from Liver Malfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Tab Store in a well closed container, Between 20°C-25°C. Protect from Moisture and Heat.

Atrovastatin should be used with caution in patients with liver disease, severe infection, heart disease, thyroid problems, uncontrolled seizures, recent major surgery, low blood pressure, any allergy or any other medical problem. Atrovastatin may cause dizziness or lightheadedness, so patient should observe caution while driving or engaging in activities requiring alertness. Atorvastatin should not be used during pregnancy or lactation.